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Regional Temperature-Sensitive Diseases and Attributable Fractions in China

National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
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Int. J. Environ. Res. Public Health 2020, 17(1), 184; https://doi.org/10.3390/ijerph17010184
Received: 10 December 2019 / Revised: 23 December 2019 / Accepted: 25 December 2019 / Published: 26 December 2019
(This article belongs to the Special Issue (In)Direct Health Effects of Extreme Weather)
Few studies have been carried out to systematically screen regional temperature-sensitive diseases. This study was aimed at systematically and comprehensively screening both high- and low-temperature-sensitive diseases by using mortality data from 17 study sites in China located in temperate and subtropical climate zones. The distributed lag nonlinear model (DLNM) was applied to quantify the association between extreme temperature and mortality to screen temperature-sensitive diseases from 18 kinds of diseases of eight disease systems. The attributable fractions (AFs) of sensitive diseases were calculated to assess the mortality burden attributable to high and low temperatures. A total of 1,380,713 records of all-cause deaths were involved. The results indicate that injuries, nervous, circulatory and respiratory diseases are sensitive to heat, with the attributable fraction accounting for 6.5%, 4.2%, 3.9% and 1.85%, respectively. Respiratory and circulatory diseases are sensitive to cold temperature, with the attributable fraction accounting for 13.3% and 11.8%, respectively. Most of the high- and low-temperature-sensitive diseases seem to have higher relative risk in study sites located in subtropical zones than in temperate zones. However, the attributable fractions for mortality of heat-related injuries were higher in temperate zones. The results of this research provide epidemiological evidence of the relative burden of mortality across two climate zones in China. View Full-Text
Keywords: extreme temperature; sensitive disease; attributable fraction; multi-region study; regional differences extreme temperature; sensitive disease; attributable fraction; multi-region study; regional differences
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Su, X.; Cheng, Y.; Wang, Y.; Liu, Y.; Li, N.; Li, Y.; Yao, X. Regional Temperature-Sensitive Diseases and Attributable Fractions in China. Int. J. Environ. Res. Public Health 2020, 17, 184.

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